Molecular weight (DA)
29kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 190-270
Specificity
CITE2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2(CITED2) Homo sapiens The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],
Function
function:Interferes with the binding of transcription factors HIF-1a and STAT2 to p300/CBP.,induction:By hypoxia and deferoxamine.,similarity:Belongs to the CITED family.,subunit:Binds to the p300/CBP CH1 region.,
Protein name
Cbp/p300-interacting transactivator 2 (MSG-related protein 1) (MRG-1) (P35srj)
Fields
>>Mitophagy - animal
Human protein sequence Database
Q99967
Mouse protein sequence database
O35740
Rat protein sequence database
Cellular localization
Nucleus . Colocalizes with EP300 in dot-like structures.
Tissue expression
Pancreas,
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