Molecular weight (DA)
33kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 130-210
Specificity
FN3K Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way, fructosamines, are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of fructosamines which may result in deglycation. [provided by RefSeq, Feb 2012],
Function
function:May initiate a process leading to the deglycation of fructoselysine and of glycated proteins. May play a role in the phosphorylation of 1-deoxy-1-morpholinofructose (DMF), fructoselysine, fructoseglycine, fructose and glycated lysozyme.,similarity:Belongs to the fructosamine kinase family.,subunit:Monomer.,tissue specificity:Expressed in erythrocytes.,
Protein name
Fructosamine-3-kinase (EC 2.7.1.-)
Human protein sequence Database
Q9H479
Mouse protein sequence database
Q9ER35
Rat protein sequence database
Cellular localization
cytosol,
Tissue expression
Widely expressed (PubMed:11522682). Expressed in erythrocytes (PubMed:11016445).