Molecular weight (DA)
40kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
S35C2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the triose-phosphate transporter protein family. This gene is regulated by oxygen tension, is induced in hypoxic trophoblast cells, and is overexpressed in ovarian cancer. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Jul 2013],
Function
function:May play an important role in the cellular response to tissue hypoxia.,induction:In hypoxic trophoblast cells.,similarity:Belongs to the TPT transporter family. SLC35C subfamily.,tissue specificity:Ubiquitously expressed although the level of expression is tissue dependent. Overexpressed in ovarian cancer.,
Gene Name
SLC35C2 C20orf5 OVCOV1 CGI-15
Protein name
Solute carrier family 35 member C2 (Ovarian cancer-overexpressed gene 1 protein)
Human protein sequence Database
Q9NQQ7
Mouse protein sequence database
Q8VCX2
Rat protein sequence database
Cellular localization
Membrane ; Multi-pass membrane protein . Golgi apparatus, cis-Golgi network membrane . Endoplasmic reticulum-Golgi intermediate compartment membrane .
Tissue expression
Ubiquitously expressed although the level of expression is tissue dependent. Overexpressed in ovarian cancer.