Molecular weight (DA)
11kD
Immunogen
Synthesized peptide derived from part region of human protein AA range: 1-50
Specificity
APOA2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008],
Function
function:May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.,mass spectrometry: PubMed:12562854,mass spectrometry:Cysteinylated ApoA-II PubMed:12562854,mass spectrometry:Heterodimer with apolipoprotein A-II(1-76) PubMed:12562854,mass spectrometry:Homodimer PubMed:12562854,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the apolipoprotein A2 family.,subunit:Homodimer; disulfide-linked. Also forms a disulfide-linked heterodimer with APOD. Interacts with HCV core protein. Interacts with APOA1BP.,tissue specificity:Plasma; synthesized in the liver and intestine.,
Protein name
Apolipoprotein A-II (Apo-AII) (ApoA-II) (Apolipoprotein A2) [Cleaved into: Truncated apolipoprotein A-II (Apolipoprotein A-II(1-76))]
Fields
>>PPAR signaling pathway;>>Cholesterol metabolism
Human protein sequence Database
P02652
Mouse protein sequence database
P09813
Rat protein sequence database
P04638
Cellular localization
Secreted .
Tissue expression
Plasma; synthesized in the liver and intestine.
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