Molecular weight (DA)
34kD
Immunogen
Synthesized peptide derived from part region of human protein AA range: 191-240
Specificity
CLC10 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
Function
function:Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells.,online information:MGL,similarity:Contains 1 C-type lectin domain.,
Gene Name
CLEC10A CLECSF13 CLECSF14 HML
Protein name
C-type lectin domain family 10 member A (C-type lectin superfamily member 14) (Macrophage lectin 2) (CD antigen CD301)
Human protein sequence Database
Q8IUN9
Mouse protein sequence database
P49300
Rat protein sequence database
P49301
Cellular localization
Membrane ; Single-pass type II membrane protein .
Tissue expression
Brain,Peripheral blood monocyte,Testis,
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