Molecular weight (DA)
47kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
BECP1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
BECN2 (Beclin 2) is a Protein Coding gene. Among its related pathways are Autophagy Pathway and Kaposi's sarcoma-associated herpesvirus infection. An important paralog of this gene is BECN1. Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover. Regulates degradation in lysosomes of a variety of G-protein coupled receptors via its interaction with GPRASP1/GASP1.
Protein name
Putative beclin-1-like protein (Beclin-1 autophagy-related pseudogene 1)
Fields
>>Autophagy - other;>>Mitophagy - animal;>>Autophagy - animal;>>Apoptosis - multiple species;>>Apelin signaling pathway;>>Alzheimer disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Spinocerebellar ataxia;>>Pathways of neurodegeneration - multiple diseases;>>Shigellosis;>>Kaposi sarcoma-associated herpesvirus infection
Human protein sequence Database
A8MW95
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasm .
Tissue expression
Present in fetal and adult brain (at protein level).
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