Molecular weight (DA)
24kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
TMED1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene belongs to the TMED (transmembrane emp24 domain-containing) protein family, which is involved in the vesicular trafficking of proteins. The protein encoded by this gene was identified by its interaction with interleukin 1 receptor-like 1 (IL1RL1) and may play a role in innate immunity. This protein lacks any similarity to other interleukin 1 ligands. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],
Function
function:Potential role in protein trafficking.,similarity:Belongs to the EMP24/GP25L family.,similarity:Contains 1 GOLD domain.,subunit:May interact with IL1RL1.,tissue specificity:Widely expressed.,
Gene Name
TMED1 IL1RL1L IL1RL1LG
Protein name
Transmembrane emp24 domain-containing protein 1 (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor-binding protein) (p24 family protein gamma-1) (Tp24) (p24gamma1)
Human protein sequence Database
Q13445
Mouse protein sequence database
Q3V009
Rat protein sequence database
Q5BK85
Cellular localization
Cell membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Golgi apparatus, cis-Golgi network membrane ; Single-pass type I membrane protein . Endoplasmic reticulum-Golgi intermediate compartment membrane ; Single-pass type I membrane protein .
Tissue expression
Widely expressed.
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