Molecular weight (DA)
16kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
HBE Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3' [provided by RefSeq, Jul 2008],
Function
function:The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin.,similarity:Belongs to the globin family.,subunit:Heterotetramer of two alpha chains and two epsilon chains in early embryonic hemoglobin Gower-2; two zeta chains and two epsilon chains in early embryonic hemoglobin Gower-1.,tissue specificity:Red blood cells.,
Protein name
Hemoglobin subunit epsilon (Epsilon-globin) (Hemoglobin epsilon chain)
Human protein sequence Database
P02100
Mouse protein sequence database
P02104
Rat protein sequence database
Cellular localization
cytosol,hemoglobin complex,blood microparticle,
Tissue expression
Red blood cells.
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