Molecular weight (DA)
50kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
TMPS5 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein that belongs to the serine protease family. Serine proteases are known to be involved in many physiological and pathological processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
Function
disease:Defects in TMPRSS5 may be a cause of deafness.,function:May play a role in hearing.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 1 SRCR domain.,tissue specificity:Brain-specific. Predominantly expressed in neurons, in their axons, and at the synapses of motoneurons in the spinal cord.,
Protein name
Transmembrane protease serine 5 (EC 3.4.21.-) (Spinesin)
Human protein sequence Database
Q9H3S3
Mouse protein sequence database
Q9ER04
Rat protein sequence database
Cellular localization
Cell membrane ; Single-pass type II membrane protein .
Tissue expression
Brain-specific. Predominantly expressed in neurons, in their axons, and at the synapses of motoneurons in the spinal cord.
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