Molecular weight (DA)
97kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
SEM6B Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the semaphorin family, a group of proteins characterized by the presence of a conserved semaphorin (sema) domain. Whereas some semaphorins are transmembrane proteins, others are secreted. Semaphorins play a major role in axon guidance. The protein encoded by this gene may be involved in both peripheral and central nervous system development. [provided by RefSeq, Jul 2008],
Function
alternative products:Additional isoforms seem to exist,function:May play a role in both peripheral and central nervous system development.,similarity:Belongs to the semaphorin family.,similarity:Contains 1 Sema domain.,
Gene Name
SEMA6B SEMAN SEMAZ UNQ1907/PRO4353
Protein name
Semaphorin-6B (Semaphorin-Z) (Sema Z)
Human protein sequence Database
Q9H3T3
Mouse protein sequence database
O54951
Rat protein sequence database
O70141
Cellular localization
Cell membrane ; Single-pass type I membrane protein .
Tissue expression
Expressed in the brain in GABAergic neurons.
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