Molecular weight (DA)
49kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 170-250
Specificity
PCOC1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity. [provided by RefSeq, Jul 2008],
Function
function:Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity.,function:C-terminal processed part of PCPE (CT-PCPE) may have an metalloproteinase inhibitory activity.,PTM:C-terminally processed at multiple positions.,similarity:Contains 1 NTR domain.,similarity:Contains 2 CUB domains.,
Protein name
Procollagen C-endopeptidase enhancer 1 (Procollagen COOH-terminal proteinase enhancer 1) (PCPE-1) (Procollagen C-proteinase enhancer 1) (Type 1 procollagen C-proteinase enhancer protein) (Type I proco
Human protein sequence Database
Q15113
Mouse protein sequence database
Q61398
Rat protein sequence database
O08628
Cellular localization
Secreted.
Tissue expression
Brain,Heart,Placenta,
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