Molecular weight (DA)
68kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 270-350
Specificity
S27A6 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the fatty acid transport protein family (FATP). FATPs are involved in the uptake of long-chain fatty acids and have unique expression patterns. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
Function
function:Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Thought to function as the predominant fatty acid protein transporter in heart.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,subcellular location:In heart is exclusively located on the sarcolemma in areas juxtaposed with small blood vessels where it colocalizes CD36.,tissue specificity:Strongly expressed in heart and localizes to cardiac myocytes. Expressed at moderate levels in placenta, testis, and adrenal glands. Expressed at very low levels in kidney, bladder and uterus.,
Gene Name
SLC27A6 ACSVL2 FACVL2 FATP1
Protein name
Long-chain fatty acid transport protein 6 (FATP-6) (Fatty acid transport protein 6) (Fatty-acid-coenzyme A ligase, very long-chain 2) (Solute carrier family 27 member 6) (Very long-chain acyl-CoA synt
Fields
>>PPAR signaling pathway;>>Insulin resistance
Human protein sequence Database
Q9Y2P4
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cell membrane, sarcolemma ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . In heart is exclusively located on the sarcolemma in areas juxtaposed with small blood vessels where it colocalizes CD36. .
Tissue expression
Strongly expressed in heart and localizes to cardiac myocytes. Expressed at moderate levels in placenta, testis, and adrenal glands. Expressed at very low levels in kidney, bladder and uterus.
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