Molecular weight (DA)
32kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 30-110
Specificity
SNAI3 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
snail family transcriptional repressor 3(SNAI3) Homo sapiens SNAI3 is a member of the SNAIL gene family, named for the Drosophila snail gene, which plays roles in mesodermal formation during embryogenesis (Katoh and Katoh, 2003 [PubMed 12579345]).[supplied by OMIM, Apr 2009],
Function
domain:Binds E-box via C2H2-type zinc finger domain.,function:Seems to inhibit myoblast differentiation. Transcriptional repressor of E-box-dependent transactivation of downstream myogenic bHLHs genes. Binds preferentially to the canonical E-box sequences 5'-CAGGTG-3' and 5'-CACCTG-3'.,similarity:Belongs to the snail C2H2-type zinc-finger protein family.,similarity:Contains 5 C2H2-type zinc fingers.,
Protein name
Zinc finger protein SNAI3 (Protein snail homolog 3) (Zinc finger protein 293)
Human protein sequence Database
Q3KNW1
Mouse protein sequence database
Q9QY31
Rat protein sequence database
Cellular localization
Nucleus .
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