Molecular weight (DA)
11kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 51-100
Specificity
BAGE2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Unknown. Candidate gene encoding tumor antigens.,miscellaneous:The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the MLL3 gene. The BAGE family was expanded by juxtacentromeric movement and/or acrocentric exchanges. BAGE family is composed of expressed genes that map to the juxtacentromeric regions of chromosomes 13 and 21 and of unexpressed gene fragments that scattered in the juxtacentromeric regions of several chromosomes, including chromosomes 9, 13, 18 and 21.,similarity:Belongs to the BAGE family.,tissue specificity:Not expressed in normal tissues except in testis. Expressed in 22% of melanomas, in bladder and lung carcinomas.,tissue specificity:Not expressed in normal tissues except in testis. Expressed in melanoma, bladder and lung carcinomas.,
Function
function:Unknown. Candidate gene encoding tumor antigens.,miscellaneous:The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the MLL3 gene. The BAGE family was expanded by juxtacentromeric movement and/or acrocentric exchanges. BAGE family is composed of expressed genes that map to the juxtacentromeric regions of chromosomes 13 and 21 and of unexpressed gene fragments that scattered in the juxtacentromeric regions of several chromosomes, including chromosomes 9, 13, 18 and 21.,similarity:Belongs to the BAGE family.,tissue specificity:Not expressed in normal tissues except in testis. Expressed in 22% of melanomas, in bladder and lung carcinomas.,tissue specificity:Not expressed in normal tissues except in testis. Expressed in melanoma, bladder and lung carcinomas.,
Protein name
B melanoma antigen 2 (Cancer/testis antigen 2.2) (CT2.2)
Human protein sequence Database
Q86Y30
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Secreted .
Tissue expression
Not expressed in normal tissues except in testis. Expressed in 22% of melanomas, in bladder and lung carcinomas.
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