Molecular weight (DA)
60kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 491-540
Specificity
FGGY Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein that phosphorylates carbohydrates such as ribulose, ribitol, and L-arabinitol. Genome-wide association studies in some populations have found an association between polymorphisms in this gene and sporadic amyotrophic lateral sclerosis, but studies of other populations have not been able to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],
Function
developmental stage:Expressed in fetal brain (at protein level).,disease:Defects in FGGY are associated with sporadic amyotrophic lateral sclerosis (ALS) [MIM:105400]. Amyotrophic lateral sclerosis is a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiology of amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors.,similarity:Belongs to the FGGY kinase family.,tissue specificity:Expressed in kidney, lung and small intestine and to a lower extent in liver and detected in cerebrospinal fluid (at protein level).,
Protein name
FGGY carbohydrate kinase domain-containing protein (EC 2.7.1.-)
Fields
>>Pentose and glucuronate interconversions;>>Metabolic pathways
Human protein sequence Database
Q96C11
Mouse protein sequence database
A2AJL3
Rat protein sequence database
Cellular localization
cytoplasm,
Tissue expression
Expressed in kidney, lung and small intestine and to a lower extent in liver and detected in cerebrospinal fluid (at protein level).
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车