Molecular weight (DA)
26kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 151-200
Specificity
DRAM1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008],
Function
autophagy, apoptosis, cell death, programmed cell death, death,
Protein name
DNA damage-regulated autophagy modulator protein 1 (Damage-regulated autophagy modulator)
Human protein sequence Database
Q8N682
Mouse protein sequence database
Q9DC58
Rat protein sequence database
Cellular localization
Lysosome membrane ; Multi-pass membrane protein .