Molecular weight (DA)
16kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 103-152
Specificity
CS012 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a small transmembrane protein. Mutations in this gene are a cause of neurodegeneration with brain iron accumulation-4 (NBIA4), but the specific function of the encoded protein is unknown. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
Protein name
Protein C19orf12
Human protein sequence Database
Q9NSK7
Mouse protein sequence database
Q8WUR0
Rat protein sequence database
Cellular localization
Mitochondrion . Mitochondrion membrane ; Single-pass membrane protein . Endoplasmic reticulum . Cytoplasm, cytosol . In response to oxidative stress, relocates to the cytosol forming aggregates that partially co-localize with mitochondria. .
Tissue expression
Brain,Lymph,Melanoma,Ovary,Stomach,
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