Molecular weight (DA)
39kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 290-370
Specificity
GPR6 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Function
function:Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Protein name
G-protein coupled receptor 6 (Sphingosine 1-phosphate receptor GPR6)
Human protein sequence Database
P46095
Mouse protein sequence database
Q6YNI2
Rat protein sequence database
P51651
Cellular localization
Cell membrane ; Multi-pass membrane protein . Detected in the intracellular compartments. It is currently unclear whether this is a cell surface or intracellular receptor.
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