Molecular weight (DA)
48kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 280-360
Specificity
OX2R Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A. [provided by RefSeq, Jan 2009],
Function
function:Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Protein name
Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2)
Fields
>>Neuroactive ligand-receptor interaction
Human protein sequence Database
O43614
Mouse protein sequence database
P58308
Rat protein sequence database
P56719
Cellular localization
Cell membrane ; Multi-pass membrane protein .
Tissue expression
Cerebellum,