Molecular weight (DA)
37kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 70-150
Specificity
LPAR6 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
lysophosphatidic acid receptor 6(LPAR6) Homo sapiens The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene aligns with an internal intron of the retinoblastoma susceptibility gene in the reverse orientation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009],
Function
similarity:Belongs to the G-protein coupled receptor 1 family.,
Protein name
Lysophosphatidic acid receptor 6 (LPA receptor 6) (LPA-6) (Oleoyl-L-alpha-lysophosphatidic acid receptor) (P2Y purinoceptor 5) (P2Y5) (Purinergic receptor 5) (RB intron encoded G-protein coupled recep
Fields
>>Phospholipase D signaling pathway;>>Neuroactive ligand-receptor interaction;>>PI3K-Akt signaling pathway;>>Pathways in cancer
Human protein sequence Database
P43657
Mouse protein sequence database
Q8BMC0
Rat protein sequence database
Q4G072
Cellular localization
Cell membrane ; Multi-pass membrane protein .
Tissue expression
Expressed ubiquitously, including in skin and hair follicle cells. Detected in both Henle's and Huxley's layers of the inner root sheath of the hair follicle and in suprabasal layers of the epidermis (at protein level). Expressed at low levels in peripheral blood leukocytes.