Molecular weight (DA)
89kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
AF1L2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation.,PTM:Tyrosine phosphorylated (by SRC).,similarity:Contains 2 PH domains.,subunit:Interacts with SRC. Interacts with LCK when tyrosine phosphorylated.,tissue specificity:Detected in spleen and thyroid, and at lower levels in kidney, brain, lung and pancreas.,
Function
function:May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation.,PTM:Tyrosine phosphorylated (by SRC).,similarity:Contains 2 PH domains.,subunit:Interacts with SRC. Interacts with LCK when tyrosine phosphorylated.,tissue specificity:Detected in spleen and thyroid, and at lower levels in kidney, brain, lung and pancreas.,
Gene Name
AFAP1L2 KIAA1914 XB130
Protein name
Actin filament-associated protein 1-like 2 (AFAP1-like protein 2)
Human protein sequence Database
Q8N4X5
Mouse protein sequence database
Q5DTU0
Rat protein sequence database
Cellular localization
Cytoplasm .
Tissue expression
Detected in spleen and thyroid, and at lower levels in kidney, brain, lung and pancreas.
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