Molecular weight (DA)
11kD
Immunogen
Synthesized peptide derived from part region of human protein AA range: 1-50
Specificity
RPRM Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDC2 activity and nuclear translocation of the CDC2 cyclin B1 complex.,induction:By TP53/p53, following X-ray irradiation.,miscellaneous:'Reprimo' signifies stop/repress.,similarity:Belongs to the reprimo family.,
Function
function:May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDC2 activity and nuclear translocation of the CDC2 cyclin B1 complex.,induction:By TP53/p53, following X-ray irradiation.,miscellaneous:'Reprimo' signifies stop/repress.,similarity:Belongs to the reprimo family.,
Protein name
Protein reprimo
Fields
>>p53 signaling pathway
Human protein sequence Database
Q9NS64
Mouse protein sequence database
Q9JJ72
Rat protein sequence database
Q5BJN9
Cellular localization
Cytoplasm . Membrane ; Single-pass membrane protein .
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