Molecular weight (DA)
16kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
ATOH7 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment. [provided by RefSeq, Dec 2011],
Function
function:Transcription factor involved in the differentiation of retinal ganglion cells.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,
Gene Name
ATOH7 ATH5 BHLHA13
Protein name
Protein atonal homolog 7 (Class A basic helix-loop-helix protein 13) (bHLHa13) (Helix-loop-helix protein hATH-5) (hATH5)
Human protein sequence Database
Q8N100
Mouse protein sequence database
Q9Z2E5
Rat protein sequence database
Cellular localization
Nucleus . Perikaryon . Cell projection, axon .
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