Molecular weight (DA)
48kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
SOX11 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. [provided by RefSeq, Jul 2008],
Function
function:Probably important in the developing nervous system. May also have a role in tissue modeling during development.,similarity:Contains 1 HMG box DNA-binding domain.,tissue specificity:Expressed mainly in the nervous system.,
Protein name
Transcription factor SOX-11
Human protein sequence Database
P35716
Mouse protein sequence database
Q7M6Y2
Rat protein sequence database
P0C1G9
Cellular localization
Nucleus .
Tissue expression
Expressed primarily in the brain and heart, with low expression in the kidney, pancreas and muscle.