Molecular weight (DA)
41kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
SUN5 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
similarity:Contains 1 Unc84 (SUN) domain.,tissue specificity:Widely expressed.,
Function
similarity:Contains 1 Unc84 (SUN) domain.,tissue specificity:Widely expressed.,
Gene Name
SUN5 SPAG4L TSARG4
Protein name
SUN domain-containing protein 5 (Sad1 and UNC84 domain-containing protein 5) (Sperm-associated antigen 4-like protein) (Testis and spermatogenesis-related gene 4 protein)
Human protein sequence Database
Q8TC36
Mouse protein sequence database
Q9DA32
Rat protein sequence database
Cellular localization
Nucleus inner membrane ; Single-pass membrane protein . Golgi apparatus . During spermiogenesis, traffics through the Golgi apparatus before reaching the round spermatid inner membrane of the nuclear envelope and later migrates to the coupling apparatus of the sperm during sperm head elongation and differentiation. In mature spermatozoa, is localized to the coupling apparatus of the sperm head and tail in the implementation fossa. .
Tissue expression
Sperm (at protein level) (PubMed:27640305). Widely expressed (PubMed:12621555). Conflictingly shown to be specifically expressed in testis (PubMed:21711156).