Molecular weight (DA)
38kD
Immunogen
Synthesized peptide derived from human ZPBP1 AA range: 176-226
Specificity
This antibody detects endogenous levels of ZPBP1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.15% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
ZPBP is one of several proteins that are thought to participate in secondary binding between acrosome-reacted sperm and the egg-specific extracellular matrix, the zona pellucida (McLeskey et al., 1998 [PubMed 9378618]).[supplied by OMIM, Aug 2008],
Function
function:May be implicated in gamete interaction during fertilization.,similarity:Belongs to the zona pellucida-binding protein Sp38 family.,
Other name
Zona pellucida-binding protein 1 (Sp38)
Human protein sequence Database
Q9BS86
Mouse protein sequence database
Q62522
Rat protein sequence database
Cellular localization
Cytoplasmic vesicle, secretory vesicle, acrosome membrane ; Peripheral membrane protein . Secreted . First localized in acrosome granule, later migrates to the inner and outer acrosomal membrane. Released after the acrosomal reaction. .
Tissue expression
Expressed specifically in testis.
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