Molecular weight (DA)
38kD
Immunogen
Synthesized peptide derived from human FEZ2 AA range: 190-240
Specificity
This antibody detects endogenous levels of FEZ2 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.34% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Other orthologs include the rat gene that encodes zygin II, which can bind to synaptotagmin. [provided by RefSeq, Jul 2008],
Function
function:Involved in axonal outgrowth and fasciculation.,similarity:Belongs to the zygin family.,subunit:Interacts with synaptotagmin.,tissue specificity:Expressed in nonneural tissues, such as heart, lung, spleen, muscle, testis, placenta and melanocytes.,
Other name
Fasciculation and elongation protein zeta-2 (Zygin II) (Zygin-2)
Human protein sequence Database
Q9UHY8
Mouse protein sequence database
Q6TYB5
Rat protein sequence database
P97578
Cellular localization
cytoplasm,axon,
Tissue expression
Expressed in nonneural tissues, such as heart, lung, spleen, muscle, testis, placenta and melanocytes.
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