Molecular weight (DA)
60kD
Immunogen
Synthesized peptide derived from human DMRT2 AA range: 315-365
Specificity
This antibody detects endogenous levels of DMRT2 at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.85% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. [provided by RefSeq, Apr 2010],
Function
similarity:Belongs to the DMRT family.,similarity:Contains 1 DM DNA-binding domain.,tissue specificity:Expressed in testis, kidney and skeletal muscle.,
Other name
Doublesex- and mab-3-related transcription factor 2 (Doublesex-like 2 protein) (DSXL-2)
Human protein sequence Database
Q9Y5R5
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Expressed in testis, kidney and skeletal muscle.
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