Molecular weight (DA)
60kD
Immunogen
Synthesized peptide derived from human EAA4 AA range: 320-370
Specificity
This antibody detects endogenous levels of EAA4 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.118% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:Transports L-glutamate and also L- and D-aspartate. Seems to act as a symport by cotransporting sodium.,similarity:Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family.,tissue specificity:Brain. Expressed densely and selectively in cell bodies of Purkinje cells.,
Other name
Excitatory amino acid transporter 4 (Sodium-dependent glutamate/aspartate transporter) (Solute carrier family 1 member 6)
Fields
>>Synaptic vesicle cycle;>>Glutamatergic synapse;>>Spinocerebellar ataxia
Human protein sequence Database
P48664
Mouse protein sequence database
O35544
Rat protein sequence database
O35921
Cellular localization
Cell membrane ; Multi-pass membrane protein .
Tissue expression
Brain. Expressed densely and selectively in cell bodies of Purkinje cells.