Molecular weight (DA)
60kD
Immunogen
Synthesized peptide derived from human PTN5 AA range: 8-58
Specificity
This antibody detects endogenous levels of PTN5 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.127% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,caution:It is uncertain whether Met-1 or Met-25 is the initiator.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.,similarity:Contains 1 tyrosine-protein phosphatase domain.,
Other name
Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Neural-specific protein-tyrosine phosphatase) (Striatum-enriched protein-tyrosine phosphatase) (STEP)
Fields
>>MAPK signaling pathway
Human protein sequence Database
P54829
Mouse protein sequence database
P54830
Rat protein sequence database
P35234
Cellular localization
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Tissue expression
Amygdala,Brain,Hippocampus,