Molecular weight (DA)
60kD
Immunogen
Synthesized peptide derived from human INSM2 AA range: 8-58
Specificity
This antibody detects endogenous levels of INSM2 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.133% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:May function as a growth suppressor or tumor suppressor in liver cells and in certain neurons.,similarity:Contains 5 C2H2-type zinc fingers.,
Gene Name
INSM2 IA6 Nbla106
Other name
Insulinoma-associated protein 2 (Zinc finger protein IA-6)
Human protein sequence Database
Q96T92
Mouse protein sequence database
Q9JMC2
Rat protein sequence database
Cellular localization
Cytoplasm . Nucleus .
Tissue expression
Expressed in heart, liver, skeletal muscle, kidney and pancreas, and, to a lesser extent, in brain, lung and spleen. In the pancreas, expressed in islet cells, including insulin- and glucagon-producing alpha- and beta-cells, but not in acinar cells (at protein level). Detected in adrenal glands, particularly in the deeper layer of the cortex (at protein level).
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