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PGTA rabbit pAb

Refer to | for labeled antibodies

Specification

BYab-08032

  • 50UL $180 100UL $255
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Host
Reactiveness
Use
Molecular weight (DA)
60kD
Immunogen
Synthesized peptide derived from human PGTA AA range: 312-362
Specificity
This antibody detects endogenous levels of PGTA at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.146% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Background
Function
catalytic activity:Geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate.,cofactor:Binds 1 zinc ion per dimer.,enzyme regulation:The enzymatic reaction requires the aid of a Rab escort protein (also called component A).,function:Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively.,similarity:Belongs to the protein prenyltransferase subunit alpha family.,similarity:Contains 6 PFTA repeats.,subunit:Heterodimer of an alpha and a beta subunit, collectively called component B.,
Gene Name
RABGGTA
Protein name
PGTA
Abbreviation
PGTA
Other name
Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha)
Fields
Human gene ID
5875
Human protein sequence Database
Q92696
Mouse gene ID
56187
Mouse protein sequence database
Q9JHK4
Rat gene ID
58983
Rat protein sequence database
Q08602
Cellular localization
plasma membrane,Rab-protein geranylgeranyltransferase complex,
Tissue expression
Fetal brain,Lung,Thymus,Tongue,
Storage
-20°C/1 year

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PGTA rabbit pAb

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