Molecular weight (DA)
85kD
Immunogen
Synthesized peptide derived from human SOX5 AA range: 43-93
Specificity
This antibody detects endogenous levels of SOX5 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.303% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
Function
function:Binds specifically to the DNA sequence 5'-AACAAT-3'. Activates transcription of COL2A1 and AGC1 in vitro.,similarity:Contains 1 HMG box DNA-binding domain.,
Other name
Transcription factor SOX-5
Human protein sequence Database
P35711
Mouse protein sequence database
P35710
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Brain,Fetal heart,Heart,Liver,Testis,
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