Molecular weight (DA)
85kD
Immunogen
Synthesized peptide derived from human GOGA1 AA range: 169-219
Specificity
This antibody detects endogenous levels of GOGA1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.320% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein is associated with Sjogren's syndrome. [provided by RefSeq, Feb 2010],
Function
disease:Antibodies against GOLGA1 are present in sera from patients with Sjoegren syndrome. Sera from patients with Sjoegren syndrome often contain antibodies that react with normal components of the Golgi complex.,domain:Extended rod-like protein with coiled-coil domains.,function:Probably involved in maintaining Golgi structure.,similarity:Contains 1 GRIP domain.,subunit:Binds RAB6A.,
Other name
Golgin subfamily A member 1 (Golgin-97)
Human protein sequence Database
Q92805
Mouse protein sequence database
Q9CW79
Rat protein sequence database
Cellular localization
Golgi apparatus membrane ; Peripheral membrane protein . Golgi apparatus, trans-Golgi network membrane . Cytoplasmic vesicle, secretory vesicle, acrosome .
Tissue expression
Brain,Cervix carcinoma,Testis,
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