Molecular weight (DA)
85kD
Immunogen
Synthesized peptide derived from human PTHD3 AA range: 244-294
Specificity
This antibody detects endogenous levels of PTHD3 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.322% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:May play a role in sperm development or sperm function.,sequence caution:Translated as stop.,similarity:Belongs to the patched family.,similarity:Contains 1 SSD (sterol-sensing) domain.,subcellular location:Localizes to the midpiece of the sperm tail.,tissue specificity:Expressed in germ cells of the testis (at protein level).,
Other name
Patched domain-containing protein 3 (Patched-related protein)
Human protein sequence Database
Q3KNS1
Mouse protein sequence database
Q0EEE2
Rat protein sequence database
Cellular localization
Cell projection, cilium, flagellum membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Localizes to the midpiece of the sperm tail. .
Tissue expression
Expressed in germ cells of the testis (at protein level) (PubMed:17904097). Detected in blood lymph, colon, small intestine, ovary, testis, prostate, thymus and spleen with highest levels in testis (PubMed:21439084).
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