Molecular weight (DA)
85kD
Immunogen
Synthesized peptide derived from human SEM4F AA range: 85-135
Specificity
This antibody detects endogenous levels of SEM4F at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.336% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a transmembrane class IV semaphorin family protein, which plays a role in neural development. This gene may be involved in neurogenesis in prostate cancer, the development of neurofibromas, and breast cancer tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012],
Function
function:Has growth cone collapse activity against retinal ganglion-cell axons.,similarity:Belongs to the semaphorin family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 PSI domain.,similarity:Contains 1 Sema domain.,
Gene Name
SEMA4F SEMAM SEMAW
Other name
Semaphorin-4F (Semaphorin-M) (Sema M) (Semaphorin-W) (Sema W)
Human protein sequence Database
O95754
Mouse protein sequence database
Q9Z123
Rat protein sequence database
Q9Z143
Cellular localization
Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse, postsynaptic density . Perikaryon . Cell projection, dendrite . Colocalizes with DLG4 at synapses. .
Tissue expression
Amygdala,Brain,Liver,
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