Immunogen
Synthesized peptide derived from human ASIC5 AA range: 412-462
Specificity
This antibody detects endogenous levels of ASIC5 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene belongs to the amiloride-sensitive Na+ channel and degenerin (NaC/DEG) family, members of which have been identified in many animal species ranging from the nematode to human. The amiloride-sensitive Na(+) channel encoded by this gene is primarily expressed in the small intestine, however, its exact function is not known. [provided by RefSeq, Jul 2008],
Function
function:Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride.,similarity:Belongs to the amiloride-sensitive sodium channel family.,subunit:Homotetramer or heterotetramer.,tissue specificity:Detected in small intestine, duodenum and jejunum. Detected at very low levels in testis and rectum.,
Gene Name
ASIC5 ACCN5 HINAC
Fields
>>Inflammatory mediator regulation of TRP channels
Human protein sequence Database
Q9NY37
Mouse protein sequence database
Q9R0Y1
Rat protein sequence database
Q9R0W5
Cellular localization
Cell membrane ; Multi-pass membrane protein .
Tissue expression
Detected in small intestine, duodenum and jejunum. Detected at very low levels in testis and rectum.