Immunogen
Synthesized peptide derived from human MLEC AA range: 165-215
Specificity
This antibody detects endogenous levels of MLEC at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes the carbohydrate-binding protein malectin which is a Type I membrane-anchored endoplasmic reticulum protein. This protein has an affinity for Glc2Man9GlcNAc2 (G2M9) N-glycans and is involved in regulating glycosylation in the endoplasmic reticulum. This protein has also been shown to interact with ribophorin I and may be involved in the directing the degradation of misfolded proteins. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],
Function
function:Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the early steps of protein N-glycosylation.,similarity:Belongs to the malectin family.,
Human protein sequence Database
Q14165
Mouse protein sequence database
Q6ZQI3
Rat protein sequence database
Q5FVQ4
Cellular localization
Endoplasmic reticulum membrane ; Single-pass type I membrane protein .
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