Immunogen
Synthesized peptide derived from human TMTC2 AA range: 184-234
Specificity
This antibody detects endogenous levels of TMTC2 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene is an integral membrane protein localized to the endoplasmic reticulum (ER). The encoded protein contains many tetratricopeptide repeats, sequences known for being involved in protein-protein interactions. This protein binds both the calcium uptake pump SERCA2B and the carbohydrate-binding chaperone calnexin, and it appears to play a role in calcium homeostasis in the ER. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016],
Function
similarity:Belongs to the TMTC family.,similarity:Contains 10 TPR repeats.,
Human protein sequence Database
Q8N394
Mouse protein sequence database
Q56A06
Rat protein sequence database
Cellular localization
Membrane ; Multi-pass membrane protein . Endoplasmic reticulum .
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