Immunogen
Synthesized peptide derived from human TF2H3 AA range: 39-89
Specificity
This antibody detects endogenous levels of TF2H3 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the TFB4 family. The encoded protein is a subunit of the core-TFIIH basal transcription factor and localizes to the nucleus. The encoded protein is involved in RNA transcription by RNA polymerase II and nucleotide excision repair and associates with the Cdk-activating kinase complex. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 14. [provided by RefSeq, Dec 2012],
Function
function:Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Anchors XPB.,similarity:Belongs to the TFB4 family.,subunit:One of the six subunits forming the core-TFIIH basal transcription factor.,
Fields
>>Basal transcription factors;>>Nucleotide excision repair;>>Viral carcinogenesis
Human protein sequence Database
Q13889
Mouse protein sequence database
Q8VD76
Rat protein sequence database
Q561R7
Cellular localization
Nucleus .
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