Immunogen
Synthesized peptide derived from human CITE1 AA range: 116-166
Specificity
This antibody detects endogenous levels of CITE1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the CREB-binding protein/p300-interacting transactivator with Asp/Glu-rich C-terminal domain (CITED) family of proteins. The encoded protein, also known as melanocyte-specific gene 1, may function as a transcriptional coactivator and may play a role in pigmentation of melanocytes. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009],
Function
function:Not known, seems to be associated with pigmentation.,similarity:Belongs to the CITED family.,subunit:Binds to RBM14.,tissue specificity:Expressed only in melanocytes and testis.,
Human protein sequence Database
Q99966
Mouse protein sequence database
P97769
Rat protein sequence database
Cellular localization
Nucleus . Cytoplasm . Shuttles between the nucleus and the cytoplasm by a nuclear export signal and (NES) in a CRM1-dependent manner.
Tissue expression
Expressed only in melanocytes and testis.