Immunogen
Synthesized peptide derived from human TXLNG AA range: 219-269
Specificity
This antibody detects endogenous levels of TXLNG at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009],
Function
function:May be involved in intracellular vesicle traffic.,similarity:Belongs to the taxilin family.,subunit:Binds to the C-terminal coiled coil region of syntaxin family members STX1A, STX3A and STX4A.,tissue specificity:Ubiquitously expressed. Expressed at high level in heart and skeletal muscle. Expressed in brain, placenta, lung, liver, kidney and pancreas.,
Gene Name
TXLNG CXorf15 ELRG LSR5
Human protein sequence Database
Q9NUQ3
Mouse protein sequence database
Q8BHN1
Rat protein sequence database
Cellular localization
Nucleus membrane . Cytoplasm, cytosol .
Tissue expression
Ubiquitously expressed. Expressed at high level in heart and skeletal muscle. Expressed in brain, placenta, lung, liver, kidney and pancreas.