Immunogen
Synthesized peptide derived from human DB123 AA range: 1-51
Specificity
This antibody detects endogenous levels of DB123 at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1：50-200. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
Defensins are cysteine-rich cationic polypeptides that are important in the host immunologic response to invading microorganisms. This antimicrobial protein is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20q11.1. Two transcript variants, one protein-coding and the other not, have been found for this gene. [provided by RefSeq, Nov 2014],
Function
function:Has antibacterial activity .,similarity:Belongs to the beta-defensin family.,
Gene Name
DEFB123 DEFB23 UNQ1963/PRO4485
Human protein sequence Database
Q8N688
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Secreted .
Tissue expression
Abundant expression in the male reproductive tract only. Abundant expressed in testis and the caput region of epididymis, but low in the corpus region.
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