Immunogen
Synthesized peptide derived from human RBSK AA range: 168-218
Specificity
This antibody detects endogenous levels of RBSK at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the carbohydrate kinase PfkB family. The encoded protein phosphorylates ribose to form ribose-5-phosphate in the presence of ATP and magnesium as a first step in ribose metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],
Function
catalytic activity:ATP + D-ribose = ADP + D-ribose 5-phosphate.,enzyme regulation:Competitively inhibited by phosphonoacetic acid, etidronate, 2-carboxethylphosphonic acid, N-(phosphonomethyl)glycine, N-(phosphonomethyl)iminodiacetic acid and clodronate.,pathway:Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.,similarity:Belongs to the carbohydrate kinase pfkB family.,
Fields
>>Pentose phosphate pathway;>>Metabolic pathways
Human protein sequence Database
Q9H477
Mouse protein sequence database
Q8R1Q9
Rat protein sequence database
Cellular localization
Cytoplasm . Nucleus .
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