Immunogen
Synthesized peptide derived from human KIF15 AA range: 974-1024
Specificity
This antibody detects endogenous levels of KIF15 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:Plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly.,similarity:Belongs to the kinesin-like protein family. KLP2 subfamily.,similarity:Contains 1 kinesin-motor domain.,subcellular location:Detected during the interphase in the cytoplasm as finely punctuate pattern and irregularly shaped dots. Detected during mitosis on the mitotic spindle. Colocalizes with TPX2 in mitosis. Localizes at the central spindle at anaphase (By similarity). Localizes at the sites of invaginating cell membranes, a position that corresponds to the location of the contractile actomyosin ring of dividing cells (By similarity). Colocalizes with actin in interphase (By similarity). Colocalizes in dendrites and in growth cone of axons with microtubules.,subunit:Interacts with MKI67 and TPX2.,tissue specificity:Expressed in testis, colon, tymus and in breast cancer.,
Gene Name
KIF15 KLP2 KNSL7
Human protein sequence Database
Q9NS87
Mouse protein sequence database
Q6P9L6
Rat protein sequence database
Q7TSP2
Cellular localization
Cytoplasm. Cytoplasm, cytoskeleton, spindle. Detected during the interphase in the cytoplasm as finely punctuate pattern and irregularly shaped dots. Detected during mitosis on the mitotic spindle. Colocalizes with TPX2 in mitosis. Localizes at the central spindle at anaphase (By similarity). Localizes at the sites of invaginating cell membranes, a position that corresponds to the location of the contractile actomyosin ring of dividing cells (By similarity). Colocalizes with actin in interphase (By similarity). Colocalizes in dendrites and in growth cone of axons with microtubules (By similarity). .
Tissue expression
Expressed in testis, colon, thymus and in breast cancer.
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