Immunogen
Synthesized peptide derived from human ABT1 AA range: 140-190
Specificity
This antibody detects endogenous levels of ABT1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA. [provided by RefSeq, Jul 2008],
Function
function:Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes.,similarity:Belongs to the ESF2/ABP1 family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Interacts with ESF1/ABTAP.,
Human protein sequence Database
Q9ULW3
Mouse protein sequence database
Q9QYL7
Rat protein sequence database
Q4KLM5
Cellular localization
Nucleus . Nucleus, nucleolus .
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