Immunogen
Synthesized peptide derived from human SPR2D AA range: 16-66
Specificity
This antibody detects endogenous levels of SPR2D at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:50-200. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.,induction:During squamous differentiation of epidermal keratinocytes.,similarity:Belongs to the cornifin (SPRR) family.,
Human protein sequence Database
P22532
Mouse protein sequence database
O70555
Rat protein sequence database
Cellular localization
Cytoplasm.