Immunogen
Synthesized peptide derived from human MB211 AA range: 73-123
Specificity
This antibody detects endogenous levels of MB211 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene is similar to the MAB-21 cell fate-determining gene found in C. elegans. It may be involved in eye and cerebellum development, and it has been proposed that expansion of a trinucleotide repeat region in the 5' UTR may play a role in a variety of psychiatric disorders. [provided by RefSeq, Oct 2008],
Function
function:Required for several aspects of embryonic development including normal development of the eye.,miscellaneous:A CAG trinucleotide repeat occurs in the 5'-UTR of this gene. This repeat has been found to be highly polymorphic, although expanded alleles have not yet been definitely linked with any phenotypic abnormality.,similarity:Belongs to the mab-21 family.,tissue specificity:Expressed in brain, cerebellum and skeletal muscle.,
Gene Name
MAB21L1 CAGR1 Nbla00126
Human protein sequence Database
Q13394
Mouse protein sequence database
O70299
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Expressed in brain, cerebellum and skeletal muscle.