Immunogen
Synthesized peptide derived from human KCNT2 AA range: 689-739
Specificity
This antibody detects endogenous levels of KCNT2 at Human/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels. Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane (By similarity). Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1.,PTM:Phosphorylated by protein kinase C. Phosphorylation of the C-terminal domain inhibits channel activity.,similarity:Belongs to the potassium channel family. Calcium-activated subfamily.,similarity:Contains 1 RCK N-terminal domain.,
Human protein sequence Database
Q6UVM3
Mouse protein sequence database
Rat protein sequence database
Q6UVM4
Cellular localization
Cell membrane ; Multi-pass membrane protein .
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