Immunogen
Synthesized peptide derived from human ARP5L AA range: 4-54
Specificity
This antibody detects endogenous levels of ARP5L at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:May function as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.,similarity:Belongs to the ARPC5 family.,subunit:May be a component of the Arp2/3 complex in which it may replace ARPC5.,
Fields
>>Endocytosis;>>Tight junction;>>Fc gamma R-mediated phagocytosis;>>Regulation of actin cytoskeleton;>>Bacterial invasion of epithelial cells;>>Pathogenic Escherichia coli infection;>>Shigellosis;>>Salmonella infection;>>Yersinia infection
Human protein sequence Database
Q9BPX5
Mouse protein sequence database
Q9D898
Rat protein sequence database
A1L108
Cellular localization
Cytoplasm, cytoskeleton .